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FEBS Lett. 2004 Jun 1;567(1):103-10.

Structural elements involved in electron-coupled proton transfer in cytochrome c oxidase.

Author information

1
Department of Biochemistry and Biophysics, Stockholm University, SE-106 91 Stockholm, Sweden. andreas@dbb.su.se

Abstract

Haem-copper oxidases are the last components of the respiratory chains in aerobic organisms. These membrane-bound enzymes energetically couple the electron transfer (eT) reactions associated with reduction of dioxygen to water, to proton pumping across the membrane. Even though the mechanism of proton pumping at the molecular level still remains to be uncovered, recent progress has presented us with the structural features of the pumping machinery and detailed information about the eT and proton-transfer reactions associated with the pumping process.

PMID:
15165901
DOI:
10.1016/j.febslet.2004.04.027
[Indexed for MEDLINE]
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