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Pediatr Dermatol. 2004 May-Jun;21(3):242-5.

The importance of screening for sight-threatening retinopathy in incontinentia pigmenti.

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Department of Dermatology, Royal Liverpool Children's Hospital, Liverpool, England.


Incontinentia pigmenti (IP) is an X-linked dominant disorder of ectodermal structures affecting the skin, hair, teeth, eyes, and central nervous system. The four classic cutaneous stages of the disorder are well known to pediatric dermatologists. However, ocular and neurologic sequelae represent the major morbidity in IP. The two patients reported here highlight some of the potential ocular manifestations of IP and emphasize the importance of early ophthalmologic assessment in this condition.

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