Eucosterol-type nortriterpenoids from Merwilla natalensis

Nivan Moodley; Dulcie A Mulholland; Neil R Crouch

doi:10.1021/np0204803

Eucosterol-type nortriterpenoids from Merwilla natalensis

J Nat Prod. 2004 May;67(5):918-20. doi: 10.1021/np0204803.

Authors

Nivan Moodley¹, Dulcie A Mulholland, Neil R Crouch

Affiliation

¹ Natural Products Research Group, School of Pure and Applied Chemistry, University of KwaZulu-Natal, Durban 4041, South Africa.

PMID: 15165167
DOI: 10.1021/np0204803

Abstract

The bulbs of Merwilla natalensis have yielded two known homoisoflavanones, the known spirocyclic homoisoflavanone, scillascillin, four known nortriterpenoids, and the new nortriterpenoid, (22R,23S)-17alpha,23-epoxy-22,29-dihydroxy-27-nor-lanost-8-en-3,24-dione (1), bisnortriterpenoid, (22R,23S)-17alpha,23-epoxy-3beta,22,24xi-trihydroxy-27,28-bisnor-lanost-8-ene (2), and trisnortriterpenoid, (23S)-17alpha,23-epoxy-3beta,24xi-dihydroxy-27,28,29-trisnor-lanost-8-ene (3). The structures of 1-3 were determined by spectroscopic methods.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Lanosterol / analogs & derivatives*
Lanosterol / chemistry*
Lanosterol / isolation & purification*
Liliaceae / chemistry*
Molecular Structure
Plant Roots / chemistry
Plants, Medicinal / chemistry*
South Africa
Stereoisomerism
Triterpenes / chemistry*
Triterpenes / isolation & purification*

Substances

Triterpenes
Lanosterol