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Cell. 2004 May 28;117(5):555-6.

Checkpoint adaptation; molecular mechanisms uncovered.

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  • 1Stanford University, Department of Molecular Pharmacology, 318 Campus Drive, Stanford, CA 94305, USA.

Abstract

Adaptation to the DNA damage checkpoint is a phenomenon long thought to be confined to the unicellular world. A new report in this issue of Cell by suggests the presence of a checkpoint adaptation pathway in Xenopus egg extracts that displays interesting molecular parallels to adaptation in yeast.

PMID:
15163402
DOI:
10.1016/j.cell.2004.05.005
[PubMed - indexed for MEDLINE]
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