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Appl Environ Microbiol. 2004 May;70(5):3146-8.

Transformation of folate-consuming Lactobacillus gasseri into a folate producer.

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1
Wageningen Centre for Food Sciences and NIZO food research, Ede, The Netherlands.

Abstract

Five genes essential for folate biosynthesis in Lactococcus lactis were cloned on a broad-host-range lactococcal vector and were transferred to the folate auxotroph Lactobacillus gasseri. As a result L. gasseri changed from a folate consumer to a folate producer. This principle can be used to increase folate levels in many fermented food products.

PMID:
15128580
PMCID:
PMC404390
[Indexed for MEDLINE]
Free PMC Article
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