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Clin Infect Dis. 2004 May 1;38(9):1328-30. Epub 2004 Apr 14.

Frequency of reduced vancomycin susceptibility and heterogeneous subpopulation in persistent or recurrent methicillin-resistant Staphylococcus aureus bacteremia.

Author information

1
Section of Infectious Diseases, Department of Medicine, St. John Hospital and Medical Center, Detroit, Michigan 48236, USA.

Abstract

Vancomycin susceptibility was checked in isolates from initial and final blood samples obtained from 22 patients with persistent or recurrent methicillin-resistant Staphylococcus aureus bacteremia. The minimum inhibitory concentration of vancomycin was determined using Etest and found to have increased in 2 pairs of isolates, and results of screening in 4 mu g vancomycin and a modified population analysis profile suggested heteroresistance in 3 isolates (13.6%). Heteroresistance is not a common cause of persistent or recurrent bacteremia.

PMID:
15127350
DOI:
10.1086/383036
[Indexed for MEDLINE]

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