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Best Pract Res Clin Rheumatol. 2004 Feb;18(1):59-80.

The transfer of a laboratory based hypothesis to a clinically useful therapy: the development of anti-TNF therapy of rheumatoid arthritis.

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1
Kennedy Institute of Rheumatology Division, Imperial College, 1 Aspenlea Road, Hammersmith, London W6 8LH, UK. m.feldmann@imperial.ac.uk

Abstract

The development of anti-TNF therapy is a key step forward in rheumatology as it is the first new therapy for based on investigating the molecular mechanisms of this disease. This chapter reviews how this discovery was made.

PMID:
15123038
DOI:
10.1016/j.berh.2003.09.010
[Indexed for MEDLINE]
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