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Nat Genet. 2004 Jun;36(6):577-9. Epub 2004 May 2.

Duplicate genes increase gene expression diversity within and between species.

Author information

1
Department of Ecology & Evolution, University of Chicago, 1101 East 57th Street, Chicago, Illinois 60637, USA.

Abstract

Using microarray gene expression data from several Drosophila species and strains, we show that duplicated genes, compared with single-copy genes, significantly increase gene expression diversity during development. We show further that duplicate genes tend to cause expression divergences between Drosophila species (or strains) to evolve faster than do single-copy genes. This conclusion is also supported by data from different yeast strains.

PMID:
15122255
DOI:
10.1038/ng1355
[Indexed for MEDLINE]

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