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Trends Cardiovasc Med. 2004 Apr;14(3):121-5.

Heart induction: embryology to cardiomyocyte regeneration.

Author information

1
Ann Foley and Mark Mercola are at the Stem Cell and Regeneration Program, The Burnham Institute, La Jolla, California, USA.

Abstract

Developmental biologists have uncovered many of the signaling proteins that are required to recruit early embryonic cells to the myocardial lineage. A detailed understanding of their function should provide insights into the difficult task of inducing embryonic stem cells to develop cardiomyocyte precursors for cell-based therapies. These proteins may also prove to be useful to stimulate progenitor cells to differentiate into cardiomyocytes within the damaged heart.

PMID:
15121161
DOI:
10.1016/j.tcm.2004.01.003
[Indexed for MEDLINE]

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