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Curr Biol. 2004 May 4;14(9):R346-8.

Mitosis: MCAK under the aura of Aurora B.

Author information

1
Molecular, Cell and Developmental Biology, Oklahoma Medical Research Foundation, 825 Northeast 13th Street, Oklahoma City, Oklahoma 73104, USA.

Abstract

Two new studies show that phosphorylation by Aurora B kinase controls the centromere localization and catalytic activity of the microtubule depolymerase MCAK. Physical tension from microtubule attachment may influence access of MCAK to Aurora B kinase and its opposing phosphatases.

PMID:
15120087
DOI:
10.1016/j.cub.2004.04.022
[Indexed for MEDLINE]
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