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Hum Hered. 1992;42(4):235-41.

Genetic markers in alcoholic liver cirrhosis.

Author information

1
Institute of Legal Medicine, University of Santiago de Compostela, Spain.

Abstract

11 genetic markers were typed in 157 individuals suffering from alcoholic cirrhosis, and compared with a random sample of healthy individuals. No significant differences were found for transferrin, specific group component, orosomucoid, esterase D, phosphogluconate dehydrogenase and adenylate kinase. Strong associations between alcoholic cirrhosis and alpha-1-antitrypsin PI*Z allele, haptoglobin HP*1 allele and acid phosphatase ACP AC phenotype were observed. The biological significance of these associations and their relationships with the development of alcoholic cirrhosis are also discussed.

PMID:
1512005
DOI:
10.1159/000154076
[Indexed for MEDLINE]

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