Send to

Choose Destination
Gene. 1992 Sep 1;118(1):121-5.

A gene encoding a superoxide dismutase of the facultative intracellular bacterium Listeria monocytogenes.

Author information

Theodor-Boveri-Institut für Biowissenschaften, Biozentrum, Universität Würzburg, Germany.


A gene (lmsod) encoding superoxide dismutase (SOD; EC of the facultative intracellular pathogen, Listeria monocytogenes, was cloned by functional complementation of an SOD-deficient Escherichia coli mutant. The nucleotide sequence was determined and the deduced amino acid (aa) sequence (202 aa) showed close similarity to manganese-containing SOD's from other organisms. Subunits of the recombinant L. monocytogenes SOD (re-SOD) and of both E. coli SODs formed enzymatically active hybrid enzymes in vivo. DNA/DNA-hybridization experiments showed that this type of recombinant re-sod gene is conserved within the genus Listeria.

[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center