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Int J Clin Pract. 2004 Mar;58(3):230-9.

Sustained efficacy and tolerability with vardenafil over 2 years of treatment in men with erectile dysfunction.

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1
Department of Urology, Medizinische Hochschule, Hannover, Germany. stief.christian@mh-hannover.de

Abstract

This randomised, double-blind study assessed the long-term efficacy and tolerability of vardenafil 10 and 20 mg in men with erectile dysfunction (ED). A total of 566 men who completed an initial 12-month treatment period entered a 12-month extension. In these men, both doses of vardenafil produced improvement in scores for the 'erectile function' Domain of the International Index of Erectile Function, evident from week 4 and maintained through 2 years. Sexual Encounter Profile diary responses indicated that following treatment, penetration was achieved on 92-94% of attempts and erections that lasted long enough for successful intercourse were achieved on 87-89% of attempts. In response to the General Assessment Question, 90-92% of patients reported improved erections with vardenafil. Most treatment-emergent events were mild and transient with no cardiovascular safety concerns. These results support the long-term efficacy, reliability and tolerability of vardenafil 10 and 20 mg in men with ED.

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PMID:
15117088
[Indexed for MEDLINE]
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