Format

Send to

Choose Destination
See comment in PubMed Commons below
Med J Aust. 2004 May 3;180(9):444-8.

Randomised controlled trial of graded exercise in chronic fatigue syndrome.

Author information

1
School of Human Movement and Exercise Science, University of Western Australia, Stirling Highway, Nedlands, WA 6009, Australia. kwallman@cyllene.uwa.edu.au

Abstract

OBJECTIVE:

To investigate whether 12 weeks of graded exercise with pacing would improve specific physiological, psychological and cognitive functions in people with chronic fatigue syndrome (CFS).

DESIGN:

Randomised controlled trial.

SETTING:

Human performance laboratory at the University of Western Australia.

PARTICIPANTS:

61 patients aged between 16 and 74 years diagnosed with CFS.

INTERVENTIONS:

Either graded exercise with pacing (32 patients) or relaxation/flexibility therapy (29 patients) performed twice a day over 12 weeks.

MAIN OUTCOME MEASURES:

Changes in any of the physiological, psychological or cognitive variables assessed.

RESULTS:

Following the graded exercise intervention, scores were improved for resting systolic blood pressure (P = 0.018), work capacity (W.kg(-1)) (P = 0.019), net blood lactate production (P = 0.036), depression (P = 0.027) and performance on a modified Stroop Colour Word test (P = 0.029). Rating of perceived exertion scores, associated with an exercise test, was lower after graded exercise (P = 0.013). No such changes were observed in the relaxation/flexibility condition, which served as an attention-placebo control.

CONCLUSIONS:

Graded exercise was associated with improvements in physical work capacity, as well as in specific psychological and cognitive variables. Improvements may be associated with the abandonment of avoidance behaviours.

PMID:
15115421
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Australasian Medical Publishing Company
    Loading ...
    Support Center