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J Proteome Res. 2004 Mar-Apr;3(2):253-60.

Implications of new proteomics strategies for biology and medicine.

Author information

1
Celera Genomics, 45 West Gude Drive, Rockville, Maryland 20850, USA. bruno.domon@celera.com

Abstract

Advances in proteomics have fundamentally changed the paradigm of discovery for drug targets and novel biomarkers. Proteomics methodologies currently used will be reviewed in this paper, including structural proteomics, quantitative proteomics, and functional proteomics. A strategy to identify differentially expressed cell surface proteins as monoclonal therapeutic targets in oncology will be discussed.

PMID:
15113101
DOI:
10.1021/pr034082c
[Indexed for MEDLINE]

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