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G Chir. 2004 Jan-Feb;25(1-2):23-6.

[The surgical treatment of nodular thyroid lesions: our experience. Analysis of 462 cases].

[Article in Italian]

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Università degli Studi di Palermo, AOUP Paolo Giaccone, Unità di Chirurgia Generale, dell'Uremico e dei Trapianti d'Organo.


Nodular thyroid lesions are the most frequent endocrine diseases in the general population. The surgical procedure is indicated for nodular thyroid tissue degeneration, or when the suppressive pharmacologic therapy is less efficient, even if sometimes both factors are associated. In Authors' study 462 patients were observed who underwent surgical procedures for thyroid diseases between January 1997-April 2003. In the thyroid pathology, either uninodular or multinodular, the surgical therapy adopted is total thyroidectomy, according to other Authors. The aim of total thyroidectomy is to avoid recurrence and simplify long term pharmacologic treatment. Although the question about the surgical approach (total thyroidectomy vs lobectomy) is still open in the case of single monolateral lesions, on the basis of their experience the Authors believe that the first is the best procedure. For diffused or malignant nodular thyroid pathology, on the contrary, total thyroidectomy is widely adopted.

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