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Immunol Today. 1992 Aug;13(8):306-14.

VDJ recombination.

Abstract

The ability of lymphocyte receptor V, D and J gene segments to rearrange generates much of the receptor diversity that is the hallmark of the immune system. Naturally, the mechanisms of immunoglobulin and T-cell receptor gene recombination are of enormous interest. Here, Fred Alt and colleagues review current understanding of the process and speculate on future findings.

PMID:
1510813
DOI:
10.1016/0167-5699(92)90043-7
[Indexed for MEDLINE]

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