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Pain Med. 2000 Dec;1(4):358-61.

Case report: limbic system activation by intravenous lidocaine in a patient with a complex regional pain syndrome and major depression.

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1
Department of Anesthesiology, Pain Management Services, Stanford University, School of Medicine, CA 94305-5117, USA. msleong@stanford.edu

Abstract

Intravenous lidocaine is used to treat various neuropathic pain states. Systemic local anesthetics have been reported to cause behavioral alteration via limbic system activation. This case report describes a dramatic behavioral change in a patient receiving intravenous lidocaine and suggests a possible use of lidocaine to discriminate somatic and affective pain characteristics.

PMID:
15101882
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