Send to

Choose Destination
See comment in PubMed Commons below
Int J Eat Disord. 2004 May;35(4):504-8.

Pathologic fear conditioning and anorexia nervosa: on the search for novel paradigms.

Author information

  • 1Eating Disorders Program, Department of Psychiatry and Neuropsychiatric Institute and Hospital, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, California, USA.


Although eating disorders have been the focus of an unprecedented explosion of clinical interest in recent years, the etiology of anorexia nervosa remains elusive. It is hypothesized that an underlying causative mechanism involves a propensity to extreme fear conditioning and greater than normal resistance to its extinction. Knowledge accrued from recent behavioral, genetic, and neuroanatomic research on anxiety may yield further insight into the pathogenesis of anorexia nervosa, which can be subjected to experimental validation using objective measures of classical fear conditioning and functional neuroimaging of brain structures mediating fear behavior.

[PubMed - indexed for MEDLINE]

LinkOut - more resources

Full Text Sources

Other Literature Sources

PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Wiley
    Loading ...
    Support Center