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Dermatol Surg. 2004 May;30(5):817-9.

Extraocular sebaceous carcinoma in a patient with Muir-Torre syndrome.

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1
Department of Dermatology, Stanford University Medical Center, Stanford, California 94305, USA.

Abstract

BACKGROUND:

Sebaceous carcinoma is a rare, aggressive neoplasm that arises from the adnexal epithelium of sebaceous glands and is commonly associated with Muir-Torre syndrome.

OBJECTIVE:

The metastatic potential of extraocular sebaceous carcinoma warrants a thorough evaluation to establish the extent of disease.

METHODS:

We describe a 55-year-old man who presented with an asymptomatic abdominal wall mass 3 years after definitive diagnosis of Muir-Torre syndrome.

RESULTS:

A biopsy of the surgical specimen revealed sebaceous carcinoma.

CONCLUSION:

Dermatologists are crucial to the early recognition and diagnosis of extraocular sebaceous carcinoma. In our patient with documented Muir-Torre syndrome, continued surveillance allowed for prompt recognition and treatment of this associated cutaneous malignancy.

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