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Cancer Causes Control. 2004 Apr;15(3):237-41.

International trends in prostate-cancer mortality: the decrease is continuing and spreading.

Author information

1
Cancer Epidemiology Unit, Queensland Cancer Fund, PO Box 201, Spring Hill QLD 4004, Australia. peterb@qcfepi.org.au

Abstract

OBJECTIVE:

To measure recent changes in prostate-cancer mortality across 24 developed countries.

METHODS:

Mortality data for men aged 50-79 years were obtained from the World Health Organisation mortality database and we assessed trends in age-standardised mortality rates using joinpoint regression models.

RESULTS:

Significant reductions in prostate-cancer mortality were observed in United Kingdom, United States, Austria, Canada, Italy, France, Germany, Australia and Spain, and downward trends were also observable in the Netherlands, Ireland and Sweden.

CONCLUSIONS:

Mortality declines for prostate cancer are now evident in 12 out of the 24 developed countries considered in this analysis. Increases in PSA screening and better treatment of early-stage disease, possibly acting in combination, remain plausible hypotheses.

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