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Gut. 2004 May;53 Suppl 4:iv58-65.

A systematic review of symptomatic outcomes used in oesophagitis drug therapy trials.

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1
Gastroenterology Unit, City Hospital, Dudley Road, Winson Green, Birmingham, UK.

Abstract

Symptoms are an important outcome for measurement in clinical trials into gastro-oesophageal reflux disease, but the optimal approach to symptom assessment has not been formally evaluated. The authors conducted a systematic review to assess how reflux symptoms have been evaluated and how well these correlate with oesophagitis healing and relapse.

PMID:
15082617
PMCID:
PMC1867781
[Indexed for MEDLINE]
Free PMC Article
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