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Curr Opin Neurobiol. 2004 Apr;14(2):198-202.

Human emotion and memory: interactions of the amygdala and hippocampal complex.

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  • 1Department of Psychology, 6 Washington Place, 8(th) floor, New York, New York 10003, USA.


The amygdala and hippocampal complex, two medial temporal lobe structures, are linked to two independent memory systems, each with unique characteristic functions. In emotional situations, these two systems interact in subtle but important ways. Specifically, the amygdala can modulate both the encoding and the storage of hippocampal-dependent memories. The hippocampal complex, by forming episodic representations of the emotional significance and interpretation of events, can influence the amygdala response when emotional stimuli are encountered. Although these are independent memory systems, they act in concert when emotion meets memory.

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