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Curr Opin Biotechnol. 2004 Apr;15(2):86-93.

Post-genomics of lactic acid bacteria and other food-grade bacteria to discover gut functionality.

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Wageningen Center for Food Sciences and Laboratory of Microbiology, Diedenweg 20, PO Box 557, 6700 AN, Wageningen, The Netherlands.


Recent years have seen an explosion in the number of complete or almost complete genomic sequences of lactic acid bacteria and other food-grade bacteria that are used in functional foods to increase the health of the consumer. These have been instrumental in the development of functional, comparative and other post-genomics approaches that provide the possibility to detect, unravel and understand their functionality in the human intestinal tract. In conjunction with other high-throughput approaches, these advances can be exploited in the functional food innovation cycle for developing new or designed probiotic and other bacterial products that impact gut health.

[Indexed for MEDLINE]

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