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Stroke. 2004 May;35(5):e97-9. Epub 2004 Apr 8.

Race-specific relationships between coronary and carotid artery calcification and carotid intimal medial thickness.

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1
Department of Public Health Sciences, Wake Forest University School of Medicine, Medical Center Blvd, Winston-Salem, NC 27157-1063, USA. lwgnkcht@wfubmc.edu

Abstract

BACKGROUND AND PURPOSE:

Calcified arterial plaque has been proposed as a subclinical marker of atherosclerosis. We compared it to a well-validated surrogate--carotid intimal medial thickness (IMT).

METHODS:

Calcified arterial plaque was measured in 2 vascular beds (coronary and carotid) by computed tomography, and common carotid artery IMT was measured by B-mode ultrasonography, in 438 participants.

RESULTS:

Calcium was positively associated with IMT (r=0.36 for coronary and r=0.45 for carotid, both P<0.0001). Correlations were attenuated with adjustment for age, sex, and diabetes.

CONCLUSIONS:

Calcified plaque in the coronary and carotid arteries is moderately associated with subclinical atherosclerosis.

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