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J Intensive Care Med. 2004 Mar-Apr;19(2):67-82.

Endocrine changes in critical illness.

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Department of Medicine, Section of Endocrinology, George Washington University School of Medicine, and Veterans Affairs Medical Center, 50 Irving St, NW, Rm GE246, Washington, DC 20422, USA.


The homeostatic corrections that have emerged in the course of human evolution to cope with catastrophic events involve a complex multisystem endeavor, of which the endocrine contribution is an integral component. Although the repertoire of endocrine changes has been probed in some detail, discerning the vulnerabilities and failure of this system is far more challenging. The ensuing endocrine topics illustrate some of the current issues reflecting attempts to gain an improved insight and clinical outcome for critical illness.

[Indexed for MEDLINE]

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