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Dev Cell. 2004 Apr;6(4):460-1.

To live or die by the sword: the regulation of apoptosis by the proteasome.

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1
Department of Molecular, Cellular, and Developmental Biology, University of Colorado, Boulder, CO 80309, USA.

Abstract

The proteasome has been implicated in the control of apoptosis by modulating the levels of both pro- and antiapoptotic molecules. A recent study published in the April 9th issue of Molecular Cell reveals that caspase-dependent inactivation of the proteasome can amplify the activation of apoptosis.

PMID:
15068786
DOI:
10.1016/s1534-5807(04)00104-2
[Indexed for MEDLINE]
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