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Zhong Yao Cai. 2003 Dec;26(12):875-7.

[Study on effect of flavonoids from oil-removed seeds of Hippophae rhamnoides on inducing apoptosis of human hepatoma cell].

[Article in Chinese]

Author information

1
Life Science School of East China Normal University, Shanghai 200062.

Abstract

OBJECTIVE:

To investigate the inhibitory and apoptosis-inducing effects of flavonoids from oil-removed seeds of Hippophae rhamnoides (FSH) on liver cancer cell line BEL-7402.

METHODS:

SRB, Wright staining, electron microscope and flow cytometry are used to study the effects of STT on BEL-7402 cell line.

RESULTS:

FSH has potent inhibitive effect on BEL-7402 cell line in a concentration-dependent manner. BEL-7402 cells exhibit typical morphological alteration of apoptosis when sub-Gl peak can be seen.

CONCLUSION:

FSH exerts its inhibitive effect on BEL-7402 cells by inducing apoptosis.

PMID:
15058208
[Indexed for MEDLINE]

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