Send to

Choose Destination
Brain Res. 2004 Mar 12;1000(1-2):40-56.

Afferent pain pathways: a neuroanatomical review.

Author information

Department of Psychobiology, Universidade Federal de São Paulo, Rua Napoleão de Barros, 925. Vila Clementino, 04024-002, Sao Paulo, SP, Brazil.


Painful experience is a complex entity made up of sensory, affective, motivational and cognitive dimensions. The neural mechanisms involved in pain perception acts in a serial and a parallel way, discriminating and locating the original stimulus and also integrating the affective feeling, involved in a special situation, with previous memories. This review examines the concepts of nociception, acute and chronic pain, and also describes the afferent pathways involved in reception, segmental processing and encephalic projection of pain stimulus. The interaction model of the cerebral cortex areas and their functional characteristics are also discussed.

[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center