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Mol Cell. 2004 Mar 26;13(6):763-4.

RelA life and death decisions.

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1
Department of Pharmacology, University of Wisconsin-Madison, 1300 University Avenue, Madison, WI 53706, USA.

Abstract

RelA is generally regarded as an activator of prosurvival gene transcription. However, in this issue of Molecular Cell, demonstrate that anticancer drugs turn RelA into an accomplice of apoptosis by instructing it to dominantly repress survival gene transcription.

PMID:
15053867
[Indexed for MEDLINE]
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