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Curr Opin Genet Dev. 1992 Jun;2(3):412-6.

Genome mapping: cDNA approaches.

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Department of Biochemistry, Oxford University, UK.


Clones of cDNAs have several practical advantages as start points for making physical maps of genomes: they are mainly single copy; they expand the map because of the introns in the genomic version of the gene; and they are conserved between species. They also address biologically important regions of the genome. Sequence information helps to identify new gene functions.

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