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Bioinformatics. 2004 Aug 12;20(12):1974-6. Epub 2004 Mar 25.

A genetic algorithm for the detection of new cis-regulatory modules in sets of coregulated genes.

Author information

1
Department of Electrical Engineering (ESAT-SCD), Katholieke Universiteit Leuven, Kasteelpark Arenberg 10, 3001 Heverlee (Leuven), Belgium. stein.aerts@esat.kuleuven.ac.be

Abstract

SUMMARY:

The implementation of a genetic algorithm is described that provides a fast method of searching for the optimal combination of transcription factor binding sites in a set of regulatory sequences.

AVAILABILITY:

The algorithm can be used transparently as a web service from within the Toucan software. Toucan can be accessed at http://www.esat.kuleuven.ac.be/~saerts/software/toucan.php. A standalone version of the software is available upon request.

PMID:
15044242
DOI:
10.1093/bioinformatics/bth179
[Indexed for MEDLINE]

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