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Curr Biol. 2004 Mar 23;14(6):R233-5.

Genome size: does bigger mean worse?

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1
Institute for Cell, Animal and Population Biology, School of Biological Sciences, University of Edinburgh, Edinburgh EH9 3JT, UK.

Abstract

Genome sizes vary enormously. This variation in DNA content correlates with effective population size, suggesting that deleterious additions to the genome can accumulate in small populations. On this view, the increased complexity of biological functions associated with large genomes partly reflects evolutionary degeneration.

PMID:
15043833
DOI:
10.1016/j.cub.2004.02.054
[Indexed for MEDLINE]
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