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Eur J Clin Nutr. 2004 Apr;58(4):621-8.

Arabinoxylan fibre improves metabolic control in people with Type II diabetes.

Author information

1
Department of Pathology, Monash Medical Centre, Victoria, Australia.

Abstract

OBJECTIVE:

To determine whether diet supplementation with arabinoxylan-rich (AX)-fibre from wheat improves glycaemic control in Type II diabetes.

DESIGN:

Randomized, crossover intervention trial.

SETTING:

Monash Medical Centre.

SUBJECTS:

A total of 15 subjects with Type II diabetes.

INTERVENTIONS:

Over two 5-week periods, subjects supplemented their usual diet with control bread and muffins (50% whole wheat, 50% white flour) (control diet) or with AX-bread and muffins (50% whole wheat, 36% white flour, 14% AX fibre) (AX diet). Subjects completed a 7-day food diary. At 0 and 5 weeks, venous blood was collected for determination of fasting and 2 h glucose, insulin, fructosamine and blood lipids. Blood pressure, body weight and body fat were also determined. A 24 h faecal sample, from 12 subjects, was weighed and analysed for faecal polysaccharide as a marker for dietary compliance.

RESULTS:

Control and AX diets were similar except the AX diet supplied an additional 15.1 (12.0-18.5) (mean (95% confidence intervals)) g/day dietary fibre (P=0.000). Consumption of the AX diet increased faecal output by 61.5 (0.2-122.8) g/day (P=0.05) on a wet weight basis and significantly lowered fasting and 2 h plasma glucose, 2 h insulin and serum fructosamine (P=0.002, 0.000, 0.015, and 0.02, respectively). Blood lipids, body weight, fat mass and blood pressure remained unchanged.

CONCLUSION:

A supplement of 15 g/day of AX-rich fibre can significantly improve glycaemic control in people with Type II diabetes.

PMID:
15042130
DOI:
10.1038/sj.ejcn.1601857
[Indexed for MEDLINE]

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