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Curr Opin Cell Biol. 2004 Feb;16(1):61-7.

Relating biochemistry and function in the myosin superfamily.

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1
Department of Molecular Biophysics and Biochemistry, Yale University, PO Box 208114, New Haven, CT 06520, USA.

Abstract

All characterized myosins share a common ATPase mechanism. However, detailed kinetic analyses suggest that modulation of the rate and equilibrium constants that define the ATPase cycle confers specific properties to these motor proteins, suiting them to specific physiological tasks. Understanding the kinetic mechanisms allows potential cellular functions of the different myosin classes and isoforms to be better defined.

PMID:
15037306
DOI:
10.1016/j.ceb.2003.11.011
[Indexed for MEDLINE]
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