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Curr Opin Microbiol. 2004 Feb;7(1):62-6.

How do neutrophils and pathogens interact?

Author information

1
Department for Cellular Microbiology, Max-Planck Institute for Infection Biology, Schumannstr. 21/22, 10117 Berlin, Germany. zychlinsky@mpiib-berlin.mpg.de

Abstract

Many pathogens can manipulate macrophages after phagocytosis yet are efficiently killed by neutrophils. This poses the question of whether neutrophils have mechanisms that enable them to specifically recognise pathogens and have pathogens evolved mechanisms to modulate neutrophil function? Here, we review recent work on neutrophils and their interaction with four different bacteria: Staphylococcus aureus, Helicobacter pylori, Anaplasma phagocytophilum and members of the Enterobacteriae family.

PMID:
15036142
DOI:
10.1016/j.mib.2003.12.004
[Indexed for MEDLINE]

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