Format

Send to

Choose Destination
Nat Rev Microbiol. 2004 Jan;2(1):23-32.

Chlamydia pneumoniae--an infectious risk factor for atherosclerosis?

Author information

1
Department of Pathobiology, Box 357238, University of Washington, Seattle, Washington 98155, USA. lacamp@u.washington.edu

Abstract

Cardiovascular disease, of which atherosclerosis is an important component, is the leading cause of death in the western world. Although there are well-defined risk factors for atherosclerosis, these factors do not account for all incidences of the disease. Because atherosclerotic processes are typified by chronic inflammatory responses, which are similar to those that are elicited by chronic infection, the role of infection in promoting or accelerating atherosclerosis has received renewed attention. This review focuses on the accumulating evidence that chronic infection with Chlamydia pneumoniae, a ubiquitous human respiratory pathogen, might contribute to atherosclerotic lesion progression.

PMID:
15035006
DOI:
10.1038/nrmicro796
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Nature Publishing Group
Loading ...
Support Center