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Annu Rev Immunol. 2004;22:405-29.

The dynamic life of natural killer cells.

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Howard Hughes Medical Institute, Rheumatology Division, Department of Medicine, Department of Pathology and Immunology, St. Louis, Missouri 63110, USA.


Natural killer (NK) cells play important roles in immunological processes, including early defense against viral infections. This review provides an overview of the dynamic in vivo life of NK cells from their development in the bone marrow to their mature peripheral responses and their ultimate demise, with particular emphasis on mouse NK cells and viral infections.

[Indexed for MEDLINE]

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