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J Cataract Refract Surg. 2004 Feb;30(2):398-402.

Wavefront- and topography-guided ablation in myopic eyes using Zyoptix.

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Dr. Agarwal's Eye Hospital and Eye Research Centre, Chennai, India.



To evaluate the results of wavefront- and topography-guided ablation in myopic eyes using Zyoptix (Bausch & Lomb).


Eye Research Center and Dr. Agarwal's Eye Hospital, Chennai, India.


This observational case study comprised 150 eyes with myopia and compound myopic astigmatism. Preoperatively, the patients had corneal topography with Orbscan IIz (Bausch & Lomb) and wavefront analysis with the Zywave aberrometer (Bausch & Lomb) in addition to the routine workup before laser in situ keratomileusis (LASIK). The results were assimilated using Zylink software (Bausch & Lomb), and a customized treatment plan was formulated. Laser in situ keratomileusis was performed with the Technolas 217 system (Bausch & Lomb). The patients were followed for at least 6 months.


The mean preoperative best corrected visual acuity (BCVA) (in decimal equivalent) was 0.83 (20/25) +/- 0.18 (SD) (range 0.33 to 1.00) and the mean postoperative (6 months) BCVA, 1.00 (20/20) +/- 0.23 (range 0.33 to 1.50). Three eyes (2%) lost 2 or more lines of best spectacle-corrected visual acuity. The safety index was 1.20. The mean preoperative uncorrected visual acuity (UCVA) was 0.06 (20/350) +/- 0.02 (range 0.01 to 0.50) and the mean postoperative UCVA, 0.88 (20/25) +/- 0.36 (range 0.08 to 1.50). The efficacy index was 14.66. The mean preoperative spherical equivalent (SE) was -5.25 +/- 1.68 diopters (D) (range -0.87 to -15.00 D) and the mean postoperative SE (6 months), -0.36 +/- 0.931 D (range -4.25 to +1.25 D). At 6 months, the UCVA was 1.00 (6/6) or better in 105 eyes (69.93%) and 0.5 (6/12) or better in 126 eyes (83.91%). The postoperative aberrations were decreased compared with the preoperative aberrations. One eye (0.66%) had a free cap during LASIK with subsequent loss of 2 lines of BCVA and induced higher-order aberrations (HOAs). Nine patients (11.2%) complained of halos at night.


Wavefront- and topography-guided LASIK leads to improve visual performance by decreasing HOAs. Scotopic visual complaints may be reduced with this method.

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