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Emerg Infect Dis. 2004 Feb;10(2):317-9.

Interferon-beta 1a and SARS coronavirus replication.

Author information

1
Virology Division, US Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland 21702, USA.

Abstract

A global outbreak of severe acute respiratory syndrome (SARS) caused by a novel coronavirus began in March 2003. The rapid emergence of SARS and the substantial illness and death it caused have made it a critical public health issue. Because no effective treatments are available, an intensive effort is under way to identify and test promising antiviral drugs. Here, we report that recombinant human interferon-beta 1a potently inhibits SARS coronavirus replication in vitro.

PMID:
15030704
PMCID:
PMC3322919
DOI:
10.3201/eid1002.030482
[Indexed for MEDLINE]
Free PMC Article

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