Podiatric physicians care for a wide spectrum of patients with neurologic illness. Often, patients with neurologic disease present to their podiatric physician with unrelated complaints that can be easily separated from their underlying neurologic condition. However, some neurologic conditions predictably lead to podiatric disease and, as such, are best treated in the context of the broader disease process. Neuropathies, spastic disorders, and cerebral palsy are examples of common neurologic disorders that can be associated with substantial podiatric manifestations; therefore, it is important for podiatric physicians to be familiar with these conditions. This article reviews the pathophysiology, clinical manifestations, and management of the common neurologic disorders affecting the foot.