Abstract
Chromatography and spectrophotometry techniques were designed to evaluate both qualitatively and quantitatively a degree of DNA-base deamination provoked by nitric acid. A possibility is shown of how to apply the above method in studying the mutagene activity of deaminating agents.
MeSH terms
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Adenine / chemistry
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Chromatography, Thin Layer
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Cytosine / chemistry
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DNA / chemistry*
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Hypoxanthine / chemistry
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Mutagenicity Tests / methods*
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Nitrous Acid / chemistry*
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Spectrometry, Fluorescence
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Uracil / chemistry
Substances
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Hypoxanthine
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Uracil
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Cytosine
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DNA
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Adenine
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Nitrous Acid