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Hepatogastroenterology. 2004 Jan-Feb;51(55):192-4.

Impact of previous multiple portoenterostomies on living donor liver transplantation for biliary atresia.

Author information

1
Liver Transplant Team, University of Tokyo, Japan. yasusuga-tky@umin.ac.jp

Abstract

BACKGROUND/AIMS:

The present study examined the impact of portoenterostomy on the morbidity and mortality of patients who later underwent living donor liver transplantation for biliary atresia.

METHODOLOGY:

Sixty-one consecutive patients from January 1996 to May 2001 were analyzed. They were divided into two groups according to the number of previous portoenterostomies: once (group A, n=26) and twice or more (group B, n=35). Preoperative status, mortality, morbidity, hospital duration and survival were examined and compared between the groups.

RESULTS:

Preoperative parameters regarding liver function and urgency status were comparable between the groups. The operation duration tended to be longer in group B than in group A (p=0.07). The blood loss and transfusion volumes in group B were greater than those in group A (p=0.03 for both comparisons). Vascular complications tended to be more frequent in group B patients. However, this difference was not significant (12% vs. 29%, p=0.06). The duration of hospitalization was longer in group B (p=0.04). Survival rates were comparable between the groups.

CONCLUSIONS:

Our surgical results suggest that multiple previous portoenterostomies might have negative short-term effects in patients who undergo living donor liver transplantation for biliary atresia.

PMID:
15011862
[Indexed for MEDLINE]

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