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Seizure. 2004 Apr;13(3):196-9.

Status epilepticus and seizures induced by iopamidol myelography.

Author information

1
Interdisciplinary Epilepsy-Center, Department of Neurology, Philipps-University Marburg, Marburg, Germany.

Abstract

PURPOSE:

To report that iopamidol myelography can induce status epilepticus (SE) in patients carrying the diagnosis of symptomatic epilepsy and to estimate the incidence of seizures in patients undergoing iopamidol myelography.

METHODS:

We retrospectively identified all patients with seizures/SE associated with 1350 iopamidol myelographies during the last 5 years at our institution. The impact of cervical versus lumbar myelography was analysed.

RESULTS:

Induced by iopamidol myelography two non-epileptic patients suffered from first generalised tonic-clonic seizures and a 67-year-old women with symptomatic epilepsy after a remote ischemic stroke developed a generalised tonic-clonic seizure evolving into a dialeptic and right nystagmus SE (i.e. complex focal status) of 5-hour duration. The incidence of seizures in non-epileptic patients was 0.15%. The incidence of seizure induction for lumbar myelography was lower than for myelographies that included the cervical subarachnoid space.

CONCLUSIONS:

Iopamidol myelography (especially if cervical) is associated with a risk of seizures in non-epileptic individuals and can induce SE in patients with epilepsy. Patients should be informed about the risk of seizure induction.

PMID:
15010060
DOI:
10.1016/S1059-1311(03)00077-3
[Indexed for MEDLINE]
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