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Diabet Med. 2004 Mar;21(3):203-7.

Type 2 diabetes mellitus: a disease of the innate immune system? An update.

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Clinical Biochemistry, University Hospital Lewisham, London, UK.


A few years ago a hypothesis was proposed suggesting that elements of the innate immune system, such as acute phase reactants, contribute to the development of Type 2 diabetes mellitus. Acute phase reactants such as C-reactive protein and sialic acid may thus predict risk of developing Type 2 diabetes mellitus, as well as being markers of diabetes microvascular and macrovascular complications. This article discusses these issues.

[Indexed for MEDLINE]

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