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Clin Infect Dis. 2004 Mar 15;38(6):910-2. Epub 2004 Feb 26.

Successful treatment of a critically ill patient with disseminated coccidioidomycosis, using adjunctive interferon-gamma.

Author information

1
Good Samaritan Hospital and Medical Center, Phoenix, Arizona, USA.

Abstract

Conventional antifungal therapy was not successful for a critically ill patient who had been hospitalized for 137 days in the intensive care unit with disseminated Coccidioides immitis infection and respiratory failure. The addition of interferon- gamma to the therapeutic regimen resulted in improvement and discharge from the hospital. Adjunctive interferon- gamma used in the successful treatment of severe coccidioidomycosis has not been reported previously.

PMID:
14999639
DOI:
10.1086/382075
[Indexed for MEDLINE]

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