In this study, a methane bioreactor-landfill system was utilized to treat municipal solid waste (MSW). Through analyzing and detecting the pollutant(CODCr) in the bioreactor-landfill system, a simulated mathematic formula of waste degradation was established. After treated with this system, the CODCr and VFA concentrations in MSW could be decreased from more than 20000 and 7000 mg.L-1 to less than 1500 and 200 mg.L-1, respectively.