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Am J Psychiatry. 2004 Mar;161(3):573-5.

Anterior cingulum abnormalities in male patients with schizophrenia determined through diffusion tensor imaging.

Author information

1
Institute of Mental Health, Peking University, Beijing, China.

Abstract

OBJECTIVE:

This study used diffusion tensor imaging to examine fractional anisotropy in the anterior cingulum and posterior cingulum bundles in patients with schizophrenia.

METHOD:

Twenty-one male patients and 20 healthy comparison men were studied.

RESULTS:

Reduced fractional anisotropy was seen for both sides of the anterior cingulum in the schizophrenia patients, who also exhibited less left-greater-than-right asymmetry in the anterior cingulum than was seen in the comparison subjects.

CONCLUSIONS:

The findings suggest structural disconnections in the anterior cingulum in patients with schizophrenia.

PMID:
14992988
DOI:
10.1176/appi.ajp.161.3.573
[Indexed for MEDLINE]

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