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Curr Biol. 2004 Feb 3;14(3):R129-38.

Regulation of notch signaling activity.

Author information

1
CNRS UMR 8542, Ecole Normale Supérieure, Paris, France. schweisg@wotan.ens.fr

Abstract

Cell-cell signalling mediated by the receptor Notch is used widely across the metazoans to determine cell fate and regulate pattern formation. Notch signals via a conserved regulated intramembrane proteolysis. Recent analyses of the cell biology of the Notch receptor have identified several fundamental mechanisms that contribute to regulate Notch signaling activity in space and time.

PMID:
14986688
[Indexed for MEDLINE]
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