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Infect Immun. 2004 Mar;72(3):1812-6.

Characterization of cytolethal distending toxin genes and expression in shiga toxin-producing Escherichia coli strains of non-O157 serogroups.

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1
Institut für Hygiene, Universitätsklinikum Münster, Zentrum für Molekularbiologie der Entzündung (ZMBE), Universität Münster, 48149 Münster, Germany. mbiela@uni-muenster.de

Abstract

We identified cytolethal distending toxin and its gene (cdt) in 17 of 340 non-O157 Shiga toxin-producing Escherichia coli (STEC) strains (serotypes O73:H18, O91:H21, O113:H21, and O153:H18), all of which were eae negative. cdt is either chromosomal and homologous to cdt-V (serotypes O73:H18, O91:H21, and O113:H21) or plasmidborne and identical to cdt-III (serotype O153:H18). Among eae-negative STEC, cdt was associated with disease (P = 0.003).

PMID:
14977993
PMCID:
PMC356029
[Indexed for MEDLINE]
Free PMC Article
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